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Abstract

Neuroendocrine carcinoma cases, more frequent in the GI tract, have rarely been reported in extrapulmonary areas. Neuroendocrine carcinoma of the bladder is one of the malignancies with a poor prognosis, which is expected to cause rapid metastases. In addition, neuroendocrine carcinoma of the bladder constitutes < 1% of all bladder carcinomas. In this study, we present two rare cases, a combined small cell neuroendocrine carcinoma–high-grade urothelial carcinoma and a large cell neuroendocrine carcinoma, diagnosed at Çanakkale Onsekiz Mart University, Research and Practice Hospital Pathology Clinic, between November 2016 and January 2017.

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