1 Sep 2018Case Report
Red cell distribution width and mean platelet volume as predictors of anastomotic dehiscence in colorectal surgery
Panagiotis Paliogiannis 1Federico Attene 1Alberto Porcu 1Maria Cossu 1Alessandro Fancellu 1Antonio Scanu 1Giorgio Ginesu 1Giuseppe Cherchi 1Pietro Niolu 2Massimiliano Coppola 3Ciriaco Carru 4Angelo Zinellu 4
Affiliations
Article Info
1 Departement of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy
2 Santissima Annunziata” Hospital of Sassari (AOU), Sassari, Italy.
3 “Nostra Signora della Mercede” Hospital of Lanusei, Lanusei, Italy
4 Department of Biomedical Sciences, University of Sassari, Sassari, Italy
Ann. Ital. Chir., 2018, 89(5), 419-424;
Published: 1 Sep 2018
Copyright © 2018 Annali Italiani di Chirurgia
This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
AIM: One of the most serious complications in modern colorectal surgery is the occurrence of an anastomotic dehiscence. The aim of this study was to evaluate the role of preoperative red cell distribution width (RDW) and mean platelet volume (MPV) as predictors of anastomotic dehiscence in elective surgery for colorectal cancer. MATERIALS AND METHODS: Forty-two patients with a clinically manifested anastomotic dehiscence after oncological col- orectal surgery, and 42 controls matched for age, sex, pathological stage and tumor localization were enrolled. Correlations between the preoperative RDW and MPV values and anastomotic dehiscence were investigated. RESULTS: Both the median RDW value (14.4 % vs 13.1%; p=0.007) and the median MPV value (8.0 fL vs 7.5 fL; p=0.037) were significantly higher in patients with anastomotic dehiscence than in those without. In multiple regression analysis only the RDW remained significantly associated with anastomotic dehiscence. CONCLUSIONS: The preoperative values of RDW may be useful in predicting anastomotic damage in elective oncological surgery.
Keywords
- Anastomotic Dehiscence
- MPV
- RDW
