1 Nov 2015Case Report
An unusual case of enoxaparin induced thrombocytopenia in intensive care unit
Enrico Giuliani 1Gabriele Melegari 1Alberto Farinetti 2Alberto Barbieri 1Anna Mattioli 3
Affiliations
Article Info
1 Department of Anesthesiology, Intensive Care Unit, University of Modena and Reggio Emilia, Modena, Italy
2 Department of Surgery, Intensive Care Unit, University of Modena and Reggio Emilia, Modena, Italy
3 Department of Life Science, Intensive Care Unit, University of Modena and Reggio Emilia, Modena, Italy
Ann. Ital. Chir., 2015, 86(6), 545-547;
Published: 1 Nov 2015
Copyright © 2015 Annali Italiani di Chirurgia
This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
OBJECTIVES: To present a case of heparin induced thrombocytopenia in a patient treated with enoxaparin. METHODS: A case of heparin-induced thrombocytopenia was examinated with a detailed platelet count analysis over the time and with detection of platelets antibodies. RESULTS: The detection of platelet antobodies and the recovery of platelet count after cessation of enoxaparin strongly support the diagnosis of heparin-induced thrombocytopenia (HIT). CONCLUSION: HIT is a severe side effects of heparin administration. It is more frequent in patients treated with unfractionated heparin however can also be induced by low molecular weight heparin. Guideline suggests the cessation of heparin administration and the treatment of patients with fondaparinux.
Keywords
- Enoxaparin
- Heparin induced thrombocytopenia
- Thrombocytopenia
