1 Nov 2012Article
Our orientation regarding the ductal carcinoma in situ of the breast
Pasquale Petronella 1Marco Scorzelli 1Marco Ferretti 1Giuseppe Perna 1Fulvio Freda 1Silvestro Canonico 1
Affiliations
Article Info
1 Department of Gerontology, Geriatrics and Metabolic Diseases, Second University of the Study of Naples
Ann. Ital. Chir., 2012, 83(6), 497-502;
Published: 1 Nov 2012
Copyright © 2012 Annali Italiani di Chirurgia
This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
AIM: The ductal carcinoma in situ is a malignant proliferation of mammary ductal epithelial cells without invasion beyond the basement membrane. The management of patients with DCIS is complex, controversial and has undergone changes over time. MATERIAL OF STUDY: We treated 65 patients diagnosed with DCIS between 2002 and 2005. We surveyed women aged between 28 and 71 years (average age 51.4), the DCIS in 16 patients appeared as a palpable mass (about 2.2 cm) group I and in 49 patients as microcalcifications detected on mammography - group II. RESULTS: The most frequent histological type was found to be the comedocarcinoma. After 3 years of follow-up, we had 3 cases of recurrence (4.6%) in patients undergoing conservative surgery, with Van Nuys Prognostic Index between 3 and 4. DISCUSSION: 15-25% of cases of breast cancer are DCIS. Most of these are comedocarcinomas. Comedo form DCIS is an insidious cancer. Surgical treatment ranges from mastectomy to excision of the lesion, often the latter, followed by radiotherapy. CONCLUSION: We prefer, with regard to surgical treatment, quadrantectomy with systematic control of the free margins. The search for the axillary sentinel node represents for us, too, the gold standard.
Keywords
- Adjuvant radiotherapy
- Conservative surgery
- Ductal carcinoma in situ (DCIS)