Analysis of variables predictive of severity in biliary peritonitis

Raimondo  Gabriele; Antonio  Bolognese; Giorgio  Toma; Luca  Impara; Marco  Conte; Pierfrancesco  Cello; Anna  Forcione; Paolo  Izzo; Virgilio  Nicolanti; Federico  Pugliese; Luciano  Izzo

1 Sep 2012Article

Raimondo Gabriele ¹Antonio Bolognese ¹Giorgio Toma ¹Luca Impara ²Marco Conte ¹Pierfrancesco Cello ¹Anna Forcione ¹Paolo Izzo ¹Virgilio Nicolanti ¹Federico Pugliese ¹Luciano Izzo ¹

Affiliations

Article Info

¹ Department of Surgery “P. Valdoni”, University of Rome “Sapienza” Medical School, Policlinico Umberto I, Rome, Italy

² Department of Radiological Sciences, University of Rome “Sapienza” Medical School, Policlinico Umberto I, Rome, Italy

Abstract

OBJECTIVE: To analyze clinical and laboratory findings in order to find variables predictive of severity of Biliary Peritonitis (BP). METHODS: Physical findings, course of illness, imaging and laboratory data were evaluated in 22 patients with BP, and statistically analysed to assess their prognostic significance. RESULTS: Serious illness and worse outcome were associated with: age > 60 years (P= 0.034), long time between onset of symptoms and treatment (P= 0.025), fever > 38°C (P= 0.009), WBC count > 17.000 cell/mm3 (P=0.043), diffuse abdominal pain (P= 0.034), and infected bile (P= 0.048). CONCLUSIONS: Most patients become severely ill due to supervening infection, while early bile drainage avoids serious complications. In addition, abdominal pain, fever and WBC count are also predictive of severity of BP.

Keywords

Abdominal pain
Bile drainage
Biliary peritonitis
Infected bile
Severity prognosis