CASTLE tumours of the thyroid Value of multiplanar imaging acquisition
Mario Musella 1, Stefano De Franciscis 2, Andrea Amorosi 2, Francesco Milone 1, Simona Truvolo 1, Alfredo Pede 1, Jens K. Kuhn 3
Affiliations
Article Info
1 General and Emergency Surgery, “Federico II” University, Naples, Italy
2 Chair of General Surgery and Chair of Pathological Anatomy, Magna Grecia University, Catanzaro, Italy
3 Fellow, Department of Medicine, Freie Universitat, Berlin, Germany
Abstract
BACKGROUND AND OBJECTIVE: Thyroid carcinomas thymus-like differentiation (CASTLE) are rare. The aim of this paper is to address a valid diagnostic and therapeutic protocol for these tumours using three exemplary cases and the previously published literature, METHODS: The routine use of Magnetic Resonance Imaging (MRI) in all cases of unclear thyroid fine needle aspiration cytology (FNAC) or in cases of multiple neck masses. RESULTS: Three cases of thyroid CASTLE tumours, finally confirmed by histology, are evaluated. All three patients remain in good conditions after an aggressive surgical approach followed by radiotherapy CONCLUSIONS: MRI should be routinely used in cases of unclear FNAC or multiple neck masses, Surgery and radiotherapy are effective to manage thyroid CASTLE tumours.
Keywords
- CASTLE
- Magnetic Resonance Imaging
- Thyroid tumours