Objective: The authors report their experience in diagno sis, treatment and ambulatorial follow up of 3 cases of obscure upper gastrointestinal bleeding by gastric antral vascular ectasia (GAVE). Experimental Design: Complete clinical report of 3 cases. Clinical and endoscopic indication, evaluation of effective ness of endoscopic treatment with bipolar elettrocoagulation and follow-up. Setting: Operative Unit of General and Thoracic Surgery. University “Paolo Giaccone” of Palermo. Intervention: Endoscopic treatment by multiple session with bipolar elettrocoagulation. No complications were registred. Results: complete recovery with “restitutio ad integrum”. No relapse were recorded at follow up. Conclusions: The objective of the treatment is to recogni ze the site of obscure bleeding and then stop it. The choi ce between pharmacological, endoscopic and surgical treat ment is individual for each patient. According to us, the endoscopic treatment is the first step in a gradual clinical approach, to detect the site of the lesion, to treat with bipo lar electrocoagulation or with Argon Plasma Coagulator (lower wall penetration and minimal risk of perforation).