Sinonasal adenocarcinoma in a patient without exposure to risk factors Case report and review of the literature
Luciano Izzo 1, Sara Izzo 1, Pierfrancesco Cello 1, Vollono Laura 1, Violante Orazia 1, Gradini Roberto 2, Paolo Izzo 1
Affiliations
Article Info
1 Department of Surgery “Pietro Valdoni”, Policlinico Umberto I “Sapienza” University of Rome, Rome, Italy
2 Department of Experimental Medicine, Sapienza University, Rome, Italy; I.R.C.C.S. Neuromed, Pozzilli, Italy
Abstract
OBJECTIVE: Sinonasal adenocarcinoma is a tumor typically associated with exposure to occupational carcinogens. The International Agency for Research on Cancer (IARC) published several data in order to classify carcinogenic power of physical-chemical agents as far as sinonasal cancer is concerned. MATERIALS AND METHODS: We report a clinical case of sinonasal adenocarcinoma observed in an 84 years old patient, without clinical history of past exposure to carcinogens, smoke and alcohol. RESULTS AND CONCLUSIONS: A sinonasal adenocarcinoma in a patient without risk factors is extremely rare. It is very important to recognize this cancer at an early stage in order to give better survival rates to the patients.
Keywords
- Carcinogens
- Intestinal-type adenocarcinoma
- Sinonasal cancer