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The use of silver nitrate for chronic wounds such as leg ulcers, as well as burns and acute wounds has already been described in literature. However there is currently conflicting evidence in the literature to support the use of silver nitrate. We present our experience on two cases with extensive co-morbidities associated, where the use of silver nitrate application reduce dramatically the size of large wounds, which eventually healed, avoiding the patients to undergone surgery. Furthermore to reduce pain and distress associated with the application we used local anaesthetic prior to applying the silver nitrate.