Synchronous ileal neuroendocrine tumor: diagnosis and treatment. A case report and review of the literature


COD: 01_2016_1179_2429 Categorie: ,

Antonino Buffone, Dario Cavallaro, Salvatore Lo Bianco, Lidia Puzzo, Pietro Caglià, Matteo Angelo Cannizzaro

Ann. Ital. Chir., 2016 87: 92-96

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INTRODUCTION: The majority of neuroendocrine tumors (NET) are located in the gastrointestinal tract (67.5%) and in
the bronchopulmonary (25.3%).
CASE REPORT: CA, female, 42 years old, profuse diarrhea about two months, cramping for increased peristalsis, vomiting
and weight loss. The patient, diagnosed with ileal neuroendocrine tumor, by colonoscopy with biopsy of lesion, therefore
came in our unit to be subjected to surgical therapy. Plasma assay Chromogranin A was performed: 160 ng / ml
(nv: 15-100 ng / ml). The patient underwent surgery of right hemicolectomy.
DISCUSSION: Neuroendocrine tumors although are rare diseases, have an increasing impact, probably by virtue of improved
diagnostic methods. In case of profuse diarrhea should be suspected a neuroendocrine tumor. Certainly the diagnosis of
certainty is given by histological examination (biopsy or resected nodule).
CONCLUSION: After surgical excision is necessary to perform the follow-up of chromogranin A, and, if not executed, perform
nuclear medicine examinations such as Octreoscan and PET.