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AIM: Spigelian Hernia (SH) is a rare ventral hernia with a high incarceration and obstruction risk. The purpose of this study is to present our experience in diagnosis and treatment of this rare hernia entity. MATERIAL AND METHODS: The retrospective demographic characteristics, diagnostic tools and the surgical techniques of 17 patients who were treated between 2000-2010 are included in the study. RESULTS: All patients had swelling and pain. All patients underwent preperitoneal mesh repair. No mortality or morbidity were recorded postoperatively. No recurrence was detected at the end of a 73 (13-115) month follow-up period. CONCLUSIONS: Spigelian Hernia is a rare entity with a wide clinical spectrum and difficulties in preoperative diagnosis. Surgical mesh repair seems to decrease the complication and recurrence rates.