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AIM: Rectal cancer shows a high incidence in older patients, however, only few reports focused exclusively on rectal cancer
with the exclusion of the surgery of the colon. This retrospective study aims to compare short-term and long-term
outcomes for rectal cancer in patients more than 75 years old with that observed in younger patients.
MATERIAL OF STUDY: Four hundred consecutive patients operated on for primary rectal adenocarcinoma were collected
in a prospective institutional database and divided into two groups: group 1 (≥ 75 years, n =98); group 2 (<75 years,
n= 302). Sphincter-saving restaurative proctectomy was the only procedure considered. Main clinical and pathological
data, morbidity, clinical anastomotic leakage, reoperation rate, 30-day mortality, overall survival, and cancer-related survival
were assessed and compared.
RESULTS: In our experience, advanced age itself is not a contraindication for surgical sphincter-saving proctetomy in rectal
cancer patients, although it is associated with higher morbidity and mortality. Overall survival is lower in patients
over 75 age, but cancer-related survival is not different between the two groups.
CONCLUSIONS: In our experience, advanced age itself is not a contraindication for surgical sphincter-saving proctetomy
in rectal cancer patients, although it is associated with higher morbidity and mortality. Overall survival is lower in
patients over 75 age, but cancer-related survival is not different between the two groups.
