Serum vascular endothelial growth factor receptor-3 levels in patients with esophageal squamous cell cancer

Main Article Content

Aziz Sümer
Ali Demir
Ahu Sarbay Kemik
Alpaslan Yavuz
Burak Suvak
Ahmet Cumhur Dülger
Sevim Purisa
Ozgur Kemik

Abstract

AIM: Esophageal cancer is one of the most aggressive tumors of the gastrointestinal tract. In this study, we quantified the serum vascular endothelial growth factor-3 (VEGFR-3) expression in patients with esophageal squamous cell carcinoma (ESCC) to evaluate the role of VEGFR-3 in ESCC.


MATERIALS AND METHODS: Ninety five patients with ESCC were studied. Pre-therapy and preoperative samples were stored and ELISA was used to designate the concentrations of VEGFR-3.


RESULTS: The serum values of VEGFR-3 were significantly higher in patients with ESCC than in healthy donors (p<0.0001).


CONCLUSIONS: The results imply a very good sensitivity of VEGFR-3 in ESCC. VEGFR-3 may be a good diagnostic biomarker for ESCC.

Article Details

How to Cite
Sümer, Aziz, et al. “Serum Vascular Endothelial Growth Factor Receptor-3 Levels in Patients With Esophageal Squamous Cell Cancer”. Annali Italiani Di Chirurgia, vol. 88, no. 1, Jan. 2017, pp. 20-25, https://annaliitalianidichirurgia.it/index.php/aic/article/view/114.
Section
Article