Review of a non-epithelial tumour of the small bowel after c-kit revolution

25.00

COD: 12_1185_2436 Categorie: ,

Enrico Fiori, Daniele Ferraro, Alessandro De Cesare, Giovanni Leone, Cecilia Barmann, Alberto Schillaci, Francesco Borrini

Ann. Ital. Chir., 2015 86: 183-185

La mia nuova descrizione qui!

Price of a print issue: €25.00

In this article, we reviewed the case of a patient who was object, in 1999, of a published case report of schwannoma
of the jejunal wall. Recently, the patient has been referred to our institution for a mass of the stomach identified by
upper gastrointestinal endoscopy. The patient underwent a wedge resection of the stomach and a histopathological diagnosis
of GIST of the stomach, based on a positive immunohistochemical staining of c-kit and CD34, was made. In
consideration of these findings, we performed immunohistochemistry for c-kit and for CD34 on the previous lesion of
the jejunal wall, which resulted strongly positive for CD117 and negative for CD34. A new diagnosis of gastrointestinal
stromal tumour (GIST) of jejunal wall with moderate risk of progression was made. The lesion was also classified,
according to the AJCC Seventh Edition, as a pT3, pN0, Stage II, GIST. This case shows the importance of a reassessment
of the diagnosis of mesenchymal neoplasm of the small intestine made before the development of anti-CD117 antibody
for a correct prognostic stratification, a better therapeutic management and a close follow-up, if necessary.

0

Utilizzando il sito, accetti l'utilizzo dei cookie da parte nostra. maggiori informazioni

Questo sito utilizza i cookie per fornire la migliore esperienza di navigazione possibile. Continuando a utilizzare questo sito senza modificare le impostazioni dei cookie o cliccando su "Accetta" permetti il loro utilizzo.

Chiudi