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The role of compression stockings in the treatment of chronic venous disease was amply demonstrated. Concerning patients
with chronic venous leg ulcers (VLUs), multi-layer bandage is the standard of care. Recently, multicomponent compression
stocking (McCS) systems for VLUs treatment and healing nowaday have been proposed. The aim of this review is
to describe and analyze current literature evidence regarding McCS used in VLUs treatment.