Minimal effective dose of povidone-iodine in abdominal surgery Our clinical experience

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COD: 01_2016_1207_2462 Categorie: ,

Orhan Gozeneli, Yusuf Yucel, Ali Akal, Alpaslan Terzi, Abdullah Ozgonul, Faik Tatli,Resit Ciftci, Mehmet Gumer, Ali Uzunkoy

Ann. Ital. Chir., 2016 87: 45-48

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Minimal effective dose of povidone-iodine in abdominal surgery. Our clinical experience
The aim of this study is to evaluate the thyroid function tests in order to examine whether 10 % of Povidone-Iodine(PI),
the medication we applied in 1/5 ratio diluted with 0.9 %NaCl, joins the systemic circulation during clean contaminated,
contaminated and dirty operations for solid organ hydatid cysts in abdominal area to avoid abscess formation
and spreading.
7 men and 6 women were included to the present study, prospectively. The mean age was 33.69(± 13.49). TSH, free
T3 (fT3) and free T4 (fT4) hormone levels were measured before the operation and at the third day of postoperative
period. Amount of used povidone-iodine for patients was recorded. As a result of statistical analysis applied, the preoperative
and post operative values were not significantly different regarding with the measured hormone levels (preTSH
vs postTSH: p= 0.984; prefT3 vs postfT3: p= 0.101; prefT4 vs postfT4: p=0.146). Thus, it has been shown that the
dose we used is effective, and it does not enters at all or at quite low levels into the systemic circulation. Patients whom
this application performed, abscess and intestinal adhesions have not been observed in our clinical experience. We recommend
the use of suggested doses of Povidone-Iodine in the presence of intraabdominal perforation and abscess or in
cases such as carrying a risk of cyst spreading to intraabdominal area in hydatid cysts.