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PURPOSE: Our study is to demonstrate the feasibility and the safety of the Minilaparoscopic Cholecystectomy. MATERIAL OF STUDY: During one year period 12 patients underwent 5mm Laparoscopic Cholecystectomy and 102 patientunderwent Mini-laparoscopic Cholecystectomy. In this study the exclusion criteria for surgery have been analyzed as well as the technical difficulties, the operation time, the duration of hospital stay, the post-surgery pain, the complications and the aesthetic results RESULTS: The operation time was 3 minutes longer for Mini-laparoscopic Cholecystectomy, the hospital stay was shorter in Mini-laparoscopic group. Patients that underwent 5mm Laparoscopic Cholecystectomy required a longer analgesic therapy. Complications occurred during the study were not related to the method. The aesthetic results were better in Minilaparoscopic Cholecystectomy due to lower scars length. Only in two cases we converted the planned Mini-laparoscopic Cholecystectomy in 5mm Laparoscopic Cholecystectomy. DISCUSSION: All the patients submitted to Mini-laparoscopic Cholecystectomy and 5mm Laparoscopic Cholecystectomy had the same therapeutic result. The Mini-laparoscopic Cholecystectomy gave advantages on post-surgery pain and recovery time. CONCLUSIONS: In our experience the Mini-laparoscopic Cholecystectomy is a safe method that guarantees the same clinical results of conventional Laparoscopic Cholecystectomy. It shows some technical difficulties, but yet this surgery is to be recommended to expert surgeons.