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AIM: The aim of this study was to report a case concerning diagnostic and management of Anorectal melanoma.MATERIAL:A 71 years old white man presented in our Institute with anal pain, tenesmus, blooding rectal during thelast five months. The ano-rectal examination showed a brownish painful mass in the anal canal. The colonscopy andendoscopy showed a big stenotic mass from anal canal to medium rectum with a diameter of approximately 90 mm.
RESULTS: Biopsy of the rectal mass was performed and the histopatological examination showed malignant ephitelioidcells, pigmented melanoma. The patient was treated by abdominoperineal resection with dissection of lymphnodes. Resultof histopatological examination was ulcerated Malignant melanoma of the anal canal, growing polypoid with spindlecells and epithelioid infiltrating the mucosa, submucosa and the internal sphincter muscle. Vascular invasion. Subtotallymph node metastasis in 3 of 17.
DISCUSSION: Anorectal melanoma is an uncommon and aggressive disease. The anorectum is the third most commonlocation of malignant melanoma after the skin and retina. Lesions are difficult to diagnose because many are amelan-otic and patients present with nonspecific complaints such as anal discomfort or rectal bleeding.After diagnosis, the main treatment available is surgical resection. Sentinel lymph node mapping has an unclear role inits management. Adjuvant therapy has long been recommended; however, there are no strong data to support its use.
CONCLUSIONS: There is no convincing evidence to indicate that abdominoperineal resection did not improve the survivalrate of patients with malignant rectal melanoma as compared to the wide local excision, while the wide local excisionhad advantages in lower surgical risk and allowing patients to avoid permanent colostomy.