Large bowel familiary cancer in patients without familiary polyposis

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COD: 137-140-2 Categorie: ,

Nicolas Condilis, Paschalia Takidou, Argyrios Papavassiliou

Ann. Ital. Chir., 2007; 78: 137-140

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treated in our Unit for colon cancer.
It is well known to day that adenocarcinoma of the colon, as well as of other organs, has been proved to occur in certain
families by a dominant trait, in the absence of any precancerous lesions.
Due to this and because none of our patients has had any of the above mentioned lesions and because their tumors
developed in the colon de novo, we have to accept that there is a hereditary predisposition in the development of familial
cancer generally, which holds for our patients too.
Because of a very high incidence of cancer, close follow-up of these families is recommended, that must start early and
completed by chromosome and immunobiologic studies for all first, second and third dergee relatives.

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