Influenza del tipo istologico sulla prognosi dei pazienti sottoposti ad intervento curativo per adenocarcinoma gastrico. Studio multicentrico italiano

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G. DE MANZONI, F. ROVIELLO, D. MARRELLI, P. MORGAGNI, A. DI LEO*, L. SARAGONI, A. DE STEFANO, F. BAZZOCCHI, E. PINTO

Ann. Ital. Chir., LXXII, 1, 2001

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Background. The prognostic significance of the histological type in gastric cancer is still debated. The correlation between intestinal-diffuse type and tumor recurrence was investigated in a prospective multicentric study which col – lects the cases from three surgical Departments of Italy. Patients and Metheds. Four-hundred and twelve patients who underwent a potentially curative resection between 1988 and 1995 were considered; 273 cases were classified as intestinal type (group A), and 139 cases as diffuse type (group B). Mixed cases were excluded from the study. All patients were included in a complete follow-up program for the early diagnosis of recurrence. Clinical, histopathological and surgical factors were examined for their influence on tumor recurrence by univariate and multivariate analysis.