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INTRODUCTION: Liposarcoma is the most frequent type of retroperitoneal sarcomas. Dedifferentiated liposarcoma is the
least common subtype and is an extremely rare tumor.
CASE REPORT: We present the case of a 53-year-old male who was referred with a giant retroperitoneal mass. The patients’
mass was deemed unresectable by the previous institution and received chemotherapy with no benefit. We macroscopically
removed the 38×32 cm mass with right nefrectomy. Pathological examination revealed dedifferentiated liposarcoma.
CONCLUSION: Surgery is the gold standart in the treatment of retroperitoneal sarcomas. Giant masses present a challenge
for the surgeon with possible major vascular injuries and multiorgan resections. Therefore it is important for these
patients to be referred for surgery without delay.
