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AIMS:This study aimed to examine the correlation between DTI, clinical assessment, and electromyography results inpatients who underwent primary median nerve repair. METHODS:Ten patients who underwent primary repair of the complete median nerve transection were included. Studyassessments were performed on both the traumatized and non-traumatized extremities and patients were followed up fora minimum duration of 11 months. Clinical assessments, (Tinnel test, static 2-point discrimination test, motor and qual-ity of life assessments), electromyography and DTI were performed. RESULTS:None of the clinical or electromyographic parameters correlated significantly with any of the diffusion tensorimaging parameters, i.e. fractional anisotropy (FA) or apparent diffusion coefficient (ADC) (p>0.05 for all). In addi-tion, The Disabilities of the Arm, Shoulder and Hand (DASH) scores did not correlate with either FA (r=0.55, p=0.098)or ADC (r=0.40, p=0.260) values. However, Tinnel positive cases (n=3) had lower relative FA when compared toTinnel negative cases (n=7) (-0.11±0.19 vs. 0.05±0.04, p=0.033). CONCLUSION: Our findings do not support the presence of relations between DTI parameters and electromyographic ormost of the clinical parameters. Further MRI studies with larger numbers of patients with complete transection of themedian nerve using the novel imaging parameters are warranted.