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Desmoplastic fibroblastoma (DF) is an extremely rare benign soft tissue tumor, prevalent in adult men, mostly arising
in deep regions of extremities. The tumor presents with a slowly growing and no recurrence or metastases after surgical
excision. Histologically, DF is characterized by a collagenous stroma that contains spindle- and stellated-shaped fibroblastic
cells positive for vimentin. Differential diagnosis with locally aggressive soft tissue tumors could be difficult. This
case report deals with the clinical, pathological and immunoistochemical features of a DF of the left thigh in a 63-years