Contrast Enhanced [99mTc] MIBI SPECT/CT In Primary Hyperparathyroidism

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COD: 2887_23_07_2018_AOP Categorie: ,

Halil Komek, Edip Erdal Yilmaz, Bahri Cakabay, Serdar Altindag, Nilufer Ozdemir,
Canan Can, Ferat Kepenek

Ann Ital Chir, Digital Edition 2018; 7
Epub Ahead of Print – July 23

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OBJECTIVE: The aim of the present study was to compare the surgical results with contrast-enhanced [99mTc] MIBI
SPECT/CT results by adding the simultaneous single phase contrast to the [99mTc] MIBI SPECT/CT examination.
METHOD: Between November 2016 and January 2018, 24 (21 female, 3 male) patients who underwent an operation
after preoperative contrast-enhanced [99mTc]MIBI SPECT/CT, and 49 asymptomatic patients (42 female, 7 male), who
did not undergo surgery, were included in the study.
RESULTS: Sensitivity and specificity rates of contrast enhanced [99mTc] MIBI SPECT / CT were 100% and 100%
when evaluated together with surgical results. The rate of detection in asymptomatic patients was found to be 93.8%.
CONCLUSIONS: With the contrast-enhanced [99mTc] MIBI SPECT/CT imaging, both high sensitivity and specificity values
were achieved in the preoperative localization of parathyroid adenomas and high detection rates were obtained in
the asymptomatic group. The use of contrast IV during the [99mTc] MIBI SPECT/CT in patients without contraindications
increased both preoperative localization rates of adenomas and detection rates of asymptomatic hyperparathyroidism
cases.