Carcinoide gastrico plurifocale associato a gastrite cronica atrofica di tipo “A”. Analisi di due casi clinici.

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COD: 2001_01_089-94 Categorie: ,

D. Moneghini, M.G. Fontana, V. Villanacci, B. Salerni

Ann. Ital. Chir., LXXII, 1, 2001

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Gastric carcinoid is a rare disease, representing less than 1% of gastric tumours and 11 – 41% of all gastrointestinal carcinoids. The recent Solcia’s classification distinguishes three subtypes of these neoplasms, which show specific clinical and pathological features. Type one arises in patients with chronic atrophic gastritis (CGA), achlorhydria, hypergastrinemia and consequent enterochromaffin-like cell hyperplasia and dysplasia. Type two is related to Zollinger Ellison syndrome and type three represents the sporadic kind. We report two cases of multifocal gastric carcinoid associated to CGA, one of them with pernicious anemia.