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BACKGROUND: Brunner’s hamartoma is a quite rare neoformation whose origin is not completely clear.
METHODS: A case of a 69-year-old man with recurrent epigastric pain and an endoscopic finding of a duodenal mass is reported.
RESULTS: The complete removal of hamartoma can give a complete remission of symptoms.
CONCLUSIONS: Hamartoma can be only diagnosed by endoscopy and histological exam; its therapy is always surgical, also in order to avoid possible malignant degeneration.