Association between neuroendocrine tumor of the ileum and two colonic primary malignancies

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Published: Oct 4, 2017
Keywords:
Neuroendocrine tumors (NETs), Progression-Free Survival (PFS), Secondary primary malignancy (SPM)

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Luca Napolitano
Unit of General and Laparoscopic Surgery, “G. d’Annunzio” University, Chieti, Italy
Valentina D’Alessandro
Unit of General and Laparoscopic Surgery, “G. d’Annunzio” University, Chieti, Italy
Domenico Risio
Unit of General and Laparoscopic Surgery, “G. d’Annunzio” University, Chieti, Italy
Camilla Marinelli
Unit of Pathology, “G. d’Annunzio” University, Chieti, Italy
Roberta Cianci
Department of Neurosciences and Imaging, Section of Radiological Imaging, ‘‘G. d’Annunzio’’ University, Chieti, Italy
Paolo Innocenti
Unit of General and Laparoscopic Surgery, “G. d’Annunzio” University, Chieti, Italy

Abstract

BACKGROUND: A high rate of association between neuroendocrine tumors (NETs) and secondary primary malignancy (SPM) has been described in literature and this association can occur either in a synchronous or a metachronous presentation. A wide range of hypothesis has been postulated to explain the high rate of association between NETs and SPM, without definitive conclusions.


 


CASE PRESENTATION: We report a case of an ileal neuroendocrine tumor found incidentally at the histologic examination of the surgical specimen in a 72 years old male underwent to right hemi colectomy for two colic adenomatous polips with high grade dysplasia.


 


CONCLUSION: Large multicentric epidemiological studies should be considered to assess the association between NETs and SPM.

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How to Cite
Napolitano, Luca, et al. “Association Between Neuroendocrine Tumor of the Ileum and Two Colonic Primary Malignancies”. Annali Italiani Di Chirurgia, vol. 6, no. October, Oct. 2017, pp. 1-5, https://annaliitalianidichirurgia.it/index.php/aic/article/view/660.
Issue
Vol. 6 No. October (2017)
Section
Case Report