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BACKGROUND: A high rate of association between neuroendocrine tumors (NETs) and secondary primary malignancy
(SPM) has been described in literature and this association can occur either in a synchronous or a metachronous presentation.
A wide range of hypothesis has been postulated to explain the high rate of association between NETs and
SPM, without definitive conclusions.
CASE PRESENTATION: We report a case of an ileal neuroendocrine tumor found incidentally at the histologic examination
of the surgical specimen in a 72 years old male underwent to right hemi colectomy for two colic adenomatous polips
with high grade dysplasia.
CONCLUSION: Large multicentric epidemiological studies should be considered to assess the association between NETs and