Addome acuto da GIST perforato del digiuno


COD: 01_2009_069-74.pdf Categorie: ,

Antonino Versaci, Antonio Macrì, Maddalena Grosso, Marialuisa Terranova, Grazia Leonello, Antonio Ieni, Giovanna Rivoli, Ciro Famulari

Ann. Ital. Chir., 2009; 80: 69-74

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The authors report on a case of voluminous perforated gastrointestinal stromal tumor (GIST) of small intestine and
make a review to the light of most recent clinicopathologic advancements. The first clinical manifestation as acute abdomen
due to their perforation extremely rare. Gastrointestinal stromal tumor (GIST) represent a rare group of multiforms
tumors with various biological behaviour.
Were identified in the past as leiomyomas, leiomyosarcomas or leiomyoblastomas, has been reclassificated on immunochemical
features, with a positive expression of Kit (CD117 antigen). Traditionally the prognostic factors of these tumour
are: mitotic rate, tumor size and anatomic site. The complete surgical resection and use of imatinib mesylate (Gleevec)
are the best available approach.