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Brunner’s gland adenoma is a rare benign tumour of the duodenum. His most common location is the posterior wall
of the duodenum near the junction of its first and second portion. It is usually small and asymptomatic often discovered
incidentally with upper gastrointestinal endoscopy, but sometimes may become large causing symptoms (haemorrhage
or intestinal obstruction). We report a rare case of a very large Brunner’s gland adenoma in a 38-year-old female presenting
with severe anaemia but without obstructive symptoms and detected by ultrasonography. The tumour was managed
by surgical removal and during a six month follow-up the patient reimaned symptom-free without any recurrence.
The literature on Brunner’s gland adenoma is reviewed.