Home E-PUBLISHED Settembre 2017 Tracheobronchopathia osteochondroplastica in recurrent retrosternal goiter. Surgical management
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Tracheobronchopathia osteochondroplastica in recurrent retrosternal goiter. Surgical management

Tracheobronchopathia osteochondroplastica in recurrent retrosternal goiter. Surgical management

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Francesco Quaglino, Enrico Mazza, Mauro Navarra, Nicola Palestini, Valentina Marchese, Riccardo Lemini, Francesca Talarico, Emilpaolo Manno
Ann Ital Chir, Digital Edition 2017 - Epub, September 4

Tracheobronchopathia osteochondroplastica (TPO) is a rare pathology characterized by a progressive segmentary
stenosis of the respiratory tract due to proliferation of osteocartilagineous nodules in the lumen of the distal part of the
trachea and large bronchial trunks. Prognosis is usually benign, but some cases with an acute progression and a lethal
outcome have been described.
Clinical presentation is non specific, the chest x-ray is generally normal and there are not typical radiological signs of
suspicion: diagnosis of TPO is usually incidental.
We report a case of TPO associated with a retrosternal recurrent goiter. The CT scan conducted to evaluate the extension
and the vascular relationships showed the characteristic lesions of the TPO with a segmental stenosis of the trachea
greater than 70%. A bronchofiberoscopy confirmed the suspect of TPO.
To date, the clinical studies carried out do not show a certain etiology, but all agree that chronic damage or chronic
inflammations could be the cause of the onset of structural anomalies of the respiratory tract
In literature, there is only a report which describes an association between TPO and thyroid pathology. It is obscure
whatever these disease could be etiologically or fortuitously associated but a relationship cannot be completely excluded.
Surgeons, anesthetists and radiologists which deal with thyroid pathology must recognize the disease, especially in the presence
of bulky retrosternal goiters, to make a correct diagnosis and provide adequate perioperative management.





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